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Phenibut HCL

Do you prefer tubs? 100g Phenibut Tub

Nootropics often work by increasing energy to boost concentration and memory. Sometimes, this can leave you feeling jittery or like your mind is running a never ending race. What if you could find a cheap nootropic that gave you a sense of calm and inner peace?

What is Phenibut HCL?

Phenibut (Beta-Phenyl-Gamma-Aminobutyric acid) is a convenient solution for a calming nootropic that helps eliminate the stress and anxiety that can hurt your mental performance. Developed in Russia, Phenibut is a derivative of the neurotransmitter GABA (binding specifically to GABAB receptors). The added phenyl group allows Phenibut to pass through the blood-brain barrier and lowers levels of stress and anxiety.[1, 2]

How Does Phenibut HCL Work? Side Effects and Benefits

So if Phenibut works as GABA in the brain, what is so important about GABA? GABA (and again, specifically GABAB) works by opening up potassium channels in a given neuron. This balances the neuron's equilibrium potential in such a way that it decreases the ability for other neurotransmitters to be released and reduces overall activity in the neuron [4].

In other words, GABA slows down the processes that the targeted neuron is responsible for. This helps to explain the potential anti-anxiety and calming side effects of Phenibut. For example, the Russian Cosmonauts used Phenibut as a way to decrease anxiety without negatively affecting mental acuity.[3]

Phenibut also increases levels of dopamine, a key neurotransmitter for feeling happy and motivated.[1]

This makes Phenibut a very well-rounded calming experience. Luckily, the dopamine activity is low enough to not produce many of the bad side effects for which some dopaminergic drugs (like amphetamines) are notorious.[1]

Phenibut Dosage

As far as using Phenibut powder in your daily nootropic stack, there is a wide range of potential. Phenibut is often used to balance out the stimulating effects of some nootropics (caffeine, ampakines, etc.), but can be used on its own for its anxiolytic properties.[1] A typical Phenibut dosage can vary from as little as 200 mg to well over 500 mg. Lower doses are more commonly used earlier in the day to reduce anxiety and any jitters caused by stimulants. User often reserve the higher doses for later in the day to combat sleeplessness.

Phenibut is a great option for anyone wanting a calm head space that still allows them to get things done.[1] Phenibut is also a very inexpensive alternative to L-theanine, an amino acid which also works through GABA and, to a lesser degree, dopamine.

People who take MAO inhibitors, some anti-epileptic drugs, or who might combine Phenibut with alcohol, should consult a health care professional before taking Phenibut.

Don't forget to check out our Phenibut capsules!


  1. Phenibut (β-Phenyl-GABA): A Tranquilizer and Nootropic Drug [pdf]
  3. Lapin, Slava. From the Inside. Luniver Press. 2009.
  4. GABA Neurotransmitter

Additional Resources

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Phenibut HCL Reviews
5 out of 5, based on 5 reviews
andy from USA earth on Sep 19, 2014
Although I've never tried any other phenibut so I cant compare to other companies products I did find this stuff to be simply an Amazing product one of the best products for depression and anxiety issues I've come across will definitely be ordering again soon.
Michael Mohrle from Clifton NJ on Sep 08, 2014
A product that really works and the best price. A little goes a long way. Power city is the best! Fast shipping and it was free! Thanks, I will order again.
Bill from Maine on Sep 06, 2014
Phenibut has been a Godsend for me!
I have held off writing a review until I had a few months experience with this item. I tried it for the calming effect to help me with diabetic neuropathy related sleeplessness (the pain is worse at night, laying in bed trying to get to sleep can be horrific for me). Amazing results there! The worst evenings are much better now!
I then read of phenibut's benefits for social anxiety and it has helped there - the big test was my daughter's wedding yesterday. Normally I would have been asking my doc for Xanax or something like it. Instead I tried phenibut and it helped a LOT! 100+ people - no problem. "Last minute" days of anticipation - quieted. I was comfortable "in my own skin". I am so pleased!
You can see that for me this product has replaced a need for Xanax type anitanxiety drugs AND probably for opiate pain relievers as well.
This is not for daily use! Take heed from the warnings here. It is a great supplement when used correctly. It can be nasty if abused. And bear in mind that I am not a doctor nor did I confer with my doctor. Do not make your decisions based on my experiences alone!
jacob from usa on Aug 22, 2014
Firstly, I'd like to say that this phenibut works just as well as the more costly "pure" powders(such as liftmode brand) and this site has it for the cheapest price I've seen.
I know its highly recommend to only use 1-3x per week but I use daily as a overall mental stabilizer(clinically bipolar/ADHD) and phenibut works 10x better than any pharmaceutical drugs I've been prescribed. It calms me down, helps my focus/clarity and overall mood. I've taken 1.5 grams daily for about 3 months and don't experience any tolerance issues that I notice. However, I do notice withdrawal effects. I become agitated and socially anxious about 20 hours after previous dose. No physical symptoms of toxic effects have happened so I feel it's much healthier than any prescribed meds I've tried. I know that if I taper my doses before stopping entirely, I won't experience any extreme withdrawals.
Abraham Lincoln from US on Aug 14, 2014
Good quality Phenibut and the COA looks good. It looks, smells, tastes, and gives the effects it should. Didn't notice any impurities. One word of caution, Phenibut should not be used as a nootropic. It's highly addictive, builds tolerance quickly, and produces bad withdrawal symptoms in a matter of days. Use 500-1000mg once a week max. There are better things out there for daily use. Be safe and enjoy. :)


Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement or nootropic. Do not take this product if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues.

Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement or nootropic, since there are many unaccounted variables, which fall outside the scope of the studies.

The reviews contained within are the opinions of contributors and are not necessarily the views or opinions of Powder City. These reviews should not be taken as fact or recommendation, and are only opinions of products that the contributors may have or may have not used. Powder City makes no warranty, implied or expressed, to the accuracy of information provided by these reviews.