6.0 /10


7.0 /10


5.0 /10


Boost Energy
Bulk Powder
Improve Focus
Improve Memory
Mental Health
Mood Support



One of the newer nootropic supplements, phenylpiracetam has the same cognitive and physical enhancing benefits as piracetam, but it is believed to be 30-60 times more potent. [29] Due to its high potency, the Olympics has banned phenylpiracetam by classifying it as a performance enhancing drug.

Phenylpiracetam was developed in Russia where it is marketed as Phenotropil. Although phenylpiracetam is only available by prescription in some countries, it is currently regulated as a nutritional supplement in the U.S. Therefore, phenylpiracetam hasn’t been approved by the FDA for therapeutic uses, but anyone can try it out. Phenylpiracetam is typically used to boost brain functions and physical strength, but it may also have uses for treating anxiety, depression and even epilepsy. [2]

Benefits and Effects

Based on human and animal studies, potential phenylpiracetam uses include:

Boosting Brain Functions

Phenylpiracetam increased rats’ chances of surviving blood flow shortages to their brains. [3] In studies of humans, year-long phenylpiracetam treatments helped stroke patients regain normal brain activity. [4] A month of phenylpiracetam treatment also improved memory and cognition in human brain disease patients. [6]

Improving Memory

Speaking of which, phenylpiracetam improves memory recollection in rats by increasing dopamine receptors in the brain. [6] Studies on humans with chronic fatigue have yielded similar results. [7] [1]

Decreasing Anxiety and Depression

Phenylpiracetam lowered anxiety and increased exploratory behavior in mice when they were introduced to new environments. [8] A month of phenylpiracetam treatment similarly reduced anxiety and depression in human patients suffering from brain damage. [5] In another study, patients with comorbid heart disease, anxiety and depressive disorders noticed a reduction in psychological symptoms over 12 weeks of treatment; however, the effectiveness of the drug seemed to diminish after 4-8 weeks. [9]

Managing Epilepsy and Seizures

Phenylpiracetam could be useful for preventing seizures related to epilepsy and other neurological conditions by facilitating better communication between brain cells. [5] In a study of 31 epilepsy patients, combining phenylpiracetam with a traditional anti-seizure drug for two months prevented seizures better than the other medication alone. [10]

Increasing Energy

A large scale study of 1,170 individuals with chronic ischemia and fatigue syndrome experienced a significant reduction in symptoms after a month of phenylpiracetam treatment. [11] Phenylpiracetam also encourages mice to be more physically active. [12]

Enhancing Athletic Performance

As mentioned above, phenylpiracetam has been banned by the Olympics due to its potential as a performance enhancing drug. While human studies in this area are lacking, rodent research suggests that phenylpiracetam temporarily enhances speed and endurance. [13]

Preventing Weight Gain

In addition to lowering blood sugar levels, phenylpiracetam slowed weight gain in obese rats. [14] Consequently, some people may take phenylpiracetam for weight loss.

Defending the Immune System

In multiple rodent studies, phenylpiracetam has helped normalize both overactive and suppressed immune systems. [15] [16] [17]

Helping Hypothyroidism

After 14 days of phenylpiracetam treatment, animals with hyperactive thyroids saw improvements in their mood and immune system functions. [18]

How It Works

We all want to improve our memory, our capacity for learning, and our cognitive ability. Likewise performing well under trying circumstances, and having increased physical stamina is something most people could benefit from. So how does Phenylpiracetam accomplish this?

Like piracetam, phenylpiracetam presumably works by boosting the amount of serotonin, dopamine and GABA receptors in the brain, which are all tied to mood and anxiety regulation. [6] By increasing alpha and beta brain waves, phenylpiracetam also promotes focus, alertness and learning. [5] It also increases production of a protein called BDNF, which protects brain cells in the hippocampus, the part of the brain responsible for memories. [19] Phenylpiracetam may work as an anti-seizure drug by reducing activation of motor cortical neurons. [20]

Phenylpiracetam vs Piracetam

The only structural difference between phenylpiracetam and piracetam is that the former contains a phenyl group, which allows it to cross the blood-brain barrier. [21] Aside from enhancing the benefits of the active ingredient, the extra phenyl group also stimulates brain activity by increasing the drug’s affinity for neurotransmitter transporters, [6]

Phenylpiracetam vs Adderall

People often compare phenylpiracetam to adderall since both drugs give users a short-term mood and energy boost. Adderall contains amphetamine and is primarily designed to treat ADHD, but some people take it for its energy accelerating effects. Given phenylpiracetam’s milder side effects, many users have found phenylpiracetam to be better for short term use. Most importantly, adderall requires a prescription in the U.S. while phenylpiracetam doesn’t. Do not take phenylpiracetam for ADHD treatment since it can be habit forming.

Phenylpiracetam vs Adrafinil and Phenylpiracetam vs Modafinil

Phenylpiracetam is also frequently compared to modafinil and its cousin, adrafinil. Whereas the latter two are great for increasing energy, they lack the cognitive benefits of racetams. Phenylpiracetam is also faster acting than the other two nootropics.


Widely regarded as one of the strongest nootropic substances available on the market today, Phenylpiracetam has become a growing buzzword for nootropic users. For anyone who wants to sharpen their mind, Phenylpiracetam powder could hold the key to mental fitness and longevity.

It is possible to acquire a tolerance to phenylpiracetam fairly quickly, so do not take it every day. [22] Treat phenylpiracetam as an occasional enhancer, not a daily supplement. Phenylpiracetam withdrawal is reportedly rough, so never exceed the recommended dose.

Most users only need 100-200mg of phenylpiracetam to feel its full effects. This amount can be safely taken up to three times per day. Due to the potential for side effects, it’s best to start with a lower phenylpiracetam dose and build up from there. [5] [23] Phenylpiracetam’s half life is about 3-5 hours, so space out your doses accordingly. [22] Athletes can take phenylpiracetam pre workout to maximize their strength, speed and endurance.


Phenylpiracetam powder tastes particularly bitter. Since phenylpiracetam is fat soluble, it doesn’t disperse well in water. It’s best to just wash it down, or mix it into a smoothie or thicker juice. Fortunately, there are phenylpiracetam capsules that are just as effective.

Phenylpiracetam is fat-soluble, but will also mix with water. It is best to take fat-soluble racetams after a meal or with a fat source such as fish oil. Your body will not absorb or benefit from a fat-soluble racetam on an empty stomach.

Phenylpiracetam (also known as Carphedon) is a derivative of the original racetam, and is estimated to be 30 to 60 times more effective [1]. A Russian development, the first mention of the effects of the substance was documented as far back as the 1980’s [31].

Phenylpiracetam can transcend the blood-brain barrier with greater ease than many others nootropics. This is good news for the consumer as the effects of the phenylpiracetam are fast acting and last longer as well.

Side Effects

Phenylpiracetam has some potential psychological side effects that you should consider. According to phenylpiracetam reviews online, some users have reported increased aggressiveness as well as suicidal thoughts after taking phenylpiracetam. [24] Therefore, it is strongly recommended that individuals with predispositions to such feelings should avoid phenylpiracetam.

The most commonly reported side effect of phenylpiracetam nootropic supplements is the infamous “racetam headache.” Choline supplements may help alleviate this symptom. [25] Insomnia is another possible reaction, so don’t take phenylpiracetam before bed.

Phenylpiracetam has most of piracetam’s side effects such as irritability and nausea. Lowering your dose can help mitigate these symptoms. [22] Keep in mind that limited research has been conducted on phenylpiracetam’s effects when combined with other drugs, so discuss your phenylpiracetam use with your doctor if you take any daily medications. No overdoses have yet been documented, but given the drug’s high potency, the possibility of phenylpiracetam toxicity is likely if taken in large amounts.


While phenylpiracetam is powerful on its own, racetams can be combined with choline supplements to further increase their effects. [26] Choline is known to help prevent “phenylpiracetam headaches.” If you need extra energy, phenylpiracetam also reportedly pairs well with caffeine, fish oil and other nootropics including sulbutiamine. [27] [28] [29] Phenylpiracetam may also go well with other racetams, but there’s no reason to combine it with piracetam since they are essentially the same drug. A phenylpiracetam-noopept stack, however, may make a synergistic combination. Just be sure to use the minimal dose of each since they are both quite potent.


How do I get past the taste of Phenylpiracetam and other nootropics?

Racetams have an extremely bitter flavor that some find intolerable. If this hinders you from using this nootropic, try phenylpiracetam capsules or use our encapsulation kit to easily cap all of your nootropics and supplements.


“I fill my own 00 capsules with 100mg phenylpiracetam and 200mg micronized creatine. Each one of these capsules lasts between 4-6 hours for me, so it requires 2 per day. The phenylpiracetam provides me with a subtle, yet noticeable stimulation that helps me to stay focused on whatever is required. Personally not used on a daily basis, I save them for days that I know are going to be long and mentally exhausting.”– Andrew B

“Excellent product, always very clean and well organized packaging. This company is the real deal. As far as effects go I usually take this 300mg a day (100mg a pill) in three different intervals. This chemical combined with Kratom make my work day soar by, all the while being extremely friendly to customers and thorough with technicalities on the job. . . I work in IT and this wonderful chemical makes me LOVE doing my job even more and helping people fix their problems. It opens up a realm where I become extremely focused, laser like precision with typing and I noticed it dramatically improves my troubleshooting techniques as well. One of my go to product here along with the Noopept, Phenibut and Alpha GPC.”– Jessica

“I love the effects of Phenylpiracetam, which for me is a definitely boosted energy level, and mood that has a tiny hint of euphoria and sharpened attention. I can’t say “focus” because it’s not a “laser” focus I get, rather more of a “creative zone” where I feel inclined to think outside the box for solutions. It’s a bit tricky to hit the right dose since you only need a bit, and when I’ve had too much it’s easy to tell – I talk too much for a while till it wears off 🙂 I stack with Noopept and Alpha GPC and try to time my schedule to have a day or 2 between uses. Personally I am very happy with this product!”– Joseph

“I was looking for something I could use while cycling off caffeine as over use causes tolerance/headaches for me. I stack phenylpiracetam with oxiracetam and choline bitartrate and the effect is almost as stimulating as a good dose of caffeine, though it is more of a mental boost than physical. It is a nice contrast though and will work well enough to allow me to reduce my days of caffeine use as I cycle back and forth between the two.”– Paul B

“I was a big fan of Adrafinil, and still am, however I didn’t want to be using it every day, not just because of increased liver load, but I notice I become a little tolerant after 4-5 days. I figured phenylpiracetam might be something to fill the gap when cycling off. I didn’t expect results anywhere near that of adrafinil, however I was pleasantly surprised. First dose and 30 minutes later I have the biggest drive to not only complete my tasks for the day, but to accomplish a superior result each time. It goes without saying this stacked with either adrafinil or noopept produces some amazing effects.”– Matthew T.

“I’ve tried all most racetams and numerous noots, as well as numerous things not sold or mentioned here. Phenylpiracetam is the best mental focus supplement, period. Maybe something better will come out but until then, this is it. I’m talking 2-3x productivity, multitasking. you can feel this one. It’s extremely mild on the body, but it does help with physical endurance too. No come down. Take it in the morning, no problems with sleep. Wears off smooth. Only downside is it needs a 2-day rest after each day you take it. I find 300mg to give the right boost without being too much. Redosing is not very effective. And you’ll need to wait a few days to get full effects again. Lasts 6-9 hours, it’s hard to tell because it wears off smooth. Perfect for powering through a day of coding or other mentally intensive tasks. I’d say most amps and other stims don’t give you this kind of quality of mental clarity, especially without the physical side effects. This is a gem.”– Josh

Additional information

Weight0.001 kg


There are no reviews yet.

Be the first to review “Phenylpiracetam”



Show less

7. 8.
Also known as:Phenotropil, Carphedon
Good for: , , , , , , ,
Stacks well with: Piracetam,Alpha GPC,Citicoline
Typical dose:100-200mg
Half Life :3-5 hours