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Goes Well With

New to Nootropics?

Do you prefer tubs? 100g Aniracetam Tub

Because of either their long history of success, or their relative inexpensiveness, or both, the racetams are the staple of the nootropic world. The glowing reputation many of these nootropics have attests to their ability to help support the brain.

While Piracetam is perhaps the most popular of all the racetams and the first to be discovered, there is a whole world of possibilities in the racetam family. The selection offers customers the ability to pick the one that works best for them.

Everyone will have their preference, and one of the racetams that is often cited as a perennial fan-favorite in Aniracetam.

What is it?


Aniracetam is fat-soluble and will therfore NOT mix well with water. It is best to take fat-soluble racetams after a meal or with a fat source such as fish oil. Your body will not absorb or benefit from a fat-soluble racetam on an empty stomach.

An N-side chain modified derivative of Piracetam, Aniracetam (1-(4-methoxybenzoyl)-2-pyrrolidinone) is a popular racetam form in the nootropic community.[1]

Aniracetam has carved out a reputation as nootropic not only for claims of being much stronger than Piracetam, but also for being an ampakine.[1]

Side Effects and Benefits

Like the other racetams, Aniracetam is a powerful nootropic. Studies have indicated its ability to shoot up cognitive test scores by as much as 30%.[1] Individuals often take it for central nervous system support and cognitive enhancement.[1]

One of the main functions of Aniracetam is on the glutamate system in the brain.[2] Glutamate is a potent neurotransmitter, but the brain happens to become easily desensitized to its presence.[2] This means that you need more and more glutamate to get the same effect.

Aniracetam has shown to decrease sensitivity to glutamate, meaning that the same amount of glutamate has more effectiveness.[2] That's why Aniracetam can increase the effects of glutamate which leads to an increase in brain activity.[2]

By slowing the kinetics of fast synaptic transmission, Aniracetam increases glutamate sensitivity.[2]

Aniracetam also appears to raise glutamate caused currents in whole-cell recordings.[2]

While the direct mechanisms are not well understood, as is the case with the racetam family in general, Aniracetam has repeatedly shown to be favorite and to have low toxicity.[1]


With about a two hour half-life, individuals typically take Aniracetam multiple times a day. Most individuals start with a 750mg Aniracetam dose 2-3 times a day with meals.

As with other racetams, many people suggest taking choline to help support and boost the beneficial Aniracetam side effects while helping you avoid headaches. Users can take Aniracetam with CDP-choline, Alpha GPC, choline bitartrate, or any other choline product.


  1. Malykh, AG, and MR Sadaie. "Piracetam And Piracetam-Like Drugs: From Basic Science To Novel Clinical Applications To CNS Disorders." Drugs 70.3 (2010): 287-312. CINAHL with Full Text. Web. 3 Sept. 2012.
  2. Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus [pdf]

Additional Resources

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Reviews for Aniracetam
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This nootropic is not considered a dietary supplement and as such should only be taken under the guidance of a doctor or in a research setting.

Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement or nootropic. Do not take this product if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues.

Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement or nootropic, since there are many unaccounted variables, which fall outside the scope of the studies.

The reviews contained within are the opinions of contributors and are not necessarily the views or opinions of Powder City. These reviews should not be taken as fact or recommendation, and are only opinions of products that the contributors may have or may have not used. Powder City makes no warranty, implied or expressed, to the accuracy of information provided by these reviews.