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Alpha-glycerophosphocholine, or Alpha GPC, is a choline supplement with dozens of documented cognitive and physical benefits.
Benefits and Effects
Promoting a Healthy Liver
Choline is vital to overall liver functions, so Alpha GPC can help heal damage caused by fatty liver disease. 
Alleviating Asthma Symptoms
Alpha GPC could improve symptoms of inflammatory illnesses like asthma. 
Enhancing Cognitive Performance
Taking choline increases acetylcholine levels, which protects against cognitive decline and nervous system degeneration.   Studies also suggest that choline supplements can improve attention and memory.  
Improving Alzheimer’s and Parkinson’s Disease Symptoms
Studies have shown that increasing choline intake has helped patients with mild Alzheimer’s and Parkinson’s disease see improvements in both cognition and motor coordination. 
Lowering Cancer Risk
Choline is necessary for breaking down homocysteine, which is associated with breast cancer, so choline supplements may lower your risk of developing certain types of cancer.  
Helping Bipolar Disorder, Autism and Schizophrenia Symptoms
Research on rodents suggests that prenatal choline supplementation reduces the risk of offspring developing autism and schizophrenia.  Choline supplements may also complement medications for treating bipolar disorder. 
Speeding Up Recovery From Brain Injuries
Choline may hasten recovery from traumatic brain injuries especially if supplements are taken regularly prior to the traumatic event. 
Boosting Athletic Performance
High levels of Alpha GPC improved athletes’ weight lifting performance.  Low choline levels have been associated with muscle damage, so supplementation can enhance your endurance by keeping your muscles strong. 
High doses of choline can curb hunger, so Alpha GPC could be helpful for individuals with strict dietary limitations. 
Breaking Down Lipids
Choline helps break down unmetabolized lipids and increases absorptive surface area in the intestines. 
Clearing Up Glaucoma Symptoms
Glaucoma patients who were given a choline supplement saw significant improvements in their eyesight. 
How It Works
Alpha GPC promotes acetylcholine production thus acting as a neuroprotectant. Alpha GPC also promotes neuronal functioning by improving communication across cell membranes.  
Since HGH stimulates cell growth and repair, many athletes take Alpha GPC before bodybuilding workouts because it improves recovery time while increasing strength and lean muscle mass. 
For athletes wishing to enhance their performance and increase HGH secretion, a dose of 300-600mg daily before working out is recommended.
For cognitive and neurological decline, daily intake of 1,200mg split into three 400mg doses seems to be most effective.
Mild side effects such as headaches, nervousness, fatigue, diarrhea and nausea have been reported.
Avoid taking Alpha GPC on an empty stomach to lessen gastrointestinal symptoms.
While choline promotes heart health, too much choline can result in a buildup of TMAO, which may heighten your risk of cardiovascular problems.