What is Phosphatidylcholine?
Fats are in many things, and most people tend to think its best not to eat them. In many cases, they might be right, but what if there was a plant fat that could improve digestive health and increase cognitive function?
Phosphatidylcholine is a hydrophobic lipid that is found in the fatty substance lecithin. Phosphatidylcholine supplements are almost always derived from the lecithin in soy.
There is a great deal of interest in Phosphatidylcholine in all of its forms. There is some evidence that certain forms of Phosphatidylcholine can improve spatial learning and memory.
Phosphatidylcholine has even shown to have positive effects on human cognition, and so has sparked a great deal of interest in the supplement world.
The possible benefits do not end there. Phosphatidylcholine also exhibits effects as a modulator of inflammation. For instance, patients suffering from Ulcerative Colitis show low levels of Phosphatidylcholine. Supplementation with Phosphatidylcholine has even shown to promote a healthy intestinal tract.
Phosphatidylcholine is a critical substance used in the process of creating other lipids that help the brain function.
Something as essential as the Omega-3 DHA, oleic acid, linoleic acid, and linolenic acid are all produced through a process called phospholipase A2-catalyzed hydrolysis. This process morphs Phosphatidyl choline into various, and important, fatty acids.
Those brain fatty acids assist synaptic transmission in the hippocampus by connecting to certain receptors. When protein kinase C interacts with pre-synaptic nicotinic acetylcholine receptors, it allows for these fatty acids to target the receptor.
Since these fatty acids interact with certain acetylcholine receptors and acetylcholine is important to cognition, these fatty acids are thus presumed to be important for learning and memory.
Phosphatidylcholine Supplements for Inflammation
Phosphatidylcholine may also be a gradual and effective anti-inflammatory, specifically for the gut. While the exact reason for this is unknown, researchers have suggested that Phosphatidyl choline might make up part of the mucus due to its hydrophobic properties, or it might facilitate in signaling the mucosa.
Some cases of gut inflammation are considered to be related to low Phosphatidylcholine levels.
Phosphatidylcholine has a wide range of doses, and since it occurs in food some people might supplement more than others. Most people take anywhere from around 400 mg to several grams a day. It is advised to start low.