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Noopept is a nootropic supplement with psychostimulatory properties. Like piracetam, Noopept enhances natural cognitive abilities. [1]. 

Benefits and Effects

Enhancing Memory And Cognition

Rats who were given Noopept learned how to perform simple tasks quicker than their peers, and results seemed to improve with repeated dosing. Since learning and memory are closely tied, Noopept may help improve both traits in humans. [2]

Alleviating Anxiety

Noopept supplements also reduced anxiety in rats. Anxiety and memory are believed to be associated, so helping one should help the other. [3]

Regulating Emotion After Brain Injuries

In a study, 53 such patients were given 10mg of Noopept twice daily for eight weeks while another group of similar patients were given 400mg of piracetam three times per day over the same time period. Noopept was more effective at reducing anxiety, irritability, headaches, sleep disturbances and daytime drowsiness. [4]

Lowering Stress

Noopept lowered stress induced protein activity in rats, so it could have potential for reducing symptoms of anxiety in humans. [5] Noopept also reduced symptoms of neurosis and learned helplessness in rodents. [6]


Noopept has demonstrated neuroprotective properties, which means that it defends brain cells against damage from amyloid toxicity, oxidative damage and mitochondrial cell death. [7] [8]


Rats with type 1 diabetes given Noopept saw increased levels of incretin, which stimulates insulin secretion. Therefore, Noopept could potentially prevent symptoms of diabetes in humans. [9]

Reducing Inflammation 

Noopept reduced inflammation in rats with bacterial infections while mice given Noopept experienced white blood cell growth and improved response to antigens. [10] [11]

Aiding Thermoregulation

In a study of 127 healthy human volunteers, Noopept helped people adapt more quickly to both hot and cold environments. It also increased subjects’ capacity to work in warm conditions. [12]

How It Works

What is Noopept Used For?

Research on how Noopept works is currently limited to animal studies. In rats, Noopept stimulates the hippocampus and hypothalamus. [15] It also increases nerve growth factors, DNA transcription factors and Alpha and Beta brain waves. [16] [17]


Noopept is extremely potent, so you don’t need very much to feel its effects. Because Noopept gets metabolized so quickly, Noopept’s half life is incredibly short.

Side Effects

The most notable adverse effect is increased blood pressure, which can cause other mild inconveniences like headaches, dizziness and fatigue.

In studies comparing Noopept and Piracetam, Noopept appears to be better tolerated by most people. [18]

Noopept withdrawal symptoms are rare, but they can include mild anxiety, depression, irritability and brain fog. [19]


Noopept, Piracetam, and Choline
(10mg of Noopept, 2g of piracetam and 300mg of Alpha GPC once or twice daily)

Noopept, Aniracetam and Sulbutiamine
(10mg of Noopept, 1g of aniracetam and 300mg of Alpha GPC once or twice daily)

Additional information

Weight0.001 kg


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Also known as:N-Phenylacetyl-L-prolylglycine ethyl ester, brand name Noopept (Russian: Ноопепт), developmental code GVS-111, omberacetam
Good for: , , , , , , , ,
Stacks well with: Citicoline
Typical dose:10 - 30mg
Half Life :30-60 minutes