Description
Chemical Information
Table of Contents
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Known Chemical Data
| Systematic (IUPAC) name | 2-(Ethylamino)-1-phenylhexan-1-one |
| Chemical Name | N-Ethylhexedrone
|
| Identifiers | |
| CAS Number | 18410-62-3 |
| ATC code | |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C14H21NO |
| Molar mass | 219.33 g·mol−1 |
| Online Synonyms | |
| Hexen NEH N-ethylnorhexedrone α-ethylaminocaprophenone N-Ethylhexedrone |
Discovery, History & Research
Discovery
N-Ethylhexedrone was first described in the literature as early as August 1969 in a series of patent applications by BOEHRINGER SOHN INGELHEIM. Patent numbers DE19651545591 19650528 were used in the official application.
History
After the first patent application was completed on a series of modified cathinones, N-Ethylhexedrone became part of a larger discover leading to the more famous MDPV or methylenedioxypyrovalerone. From around 2010, N-Ethylhexedrone has been made available to the research chemical community and has been sold online for this purpose.
Since then, various countries including the UK, Japan and Sweden have since made it illegal and placed it their respective banned substances lists.
Research
There is very little research conducted on N-Ethylhexedrone to date. Most of the studies published are identifiying the forensic and toxicological identification of the novel compound found in “legal high” samples. A list of some of the more notable research conducted on N-Ethylhexedrone can be found below:
http://nsddb.eu/substance/615/N-Ethylhexedrone – Chemical Structural Data
Chemical Structural Data
As a substituted cathinone and featuring a phenethylamine sore, N-Ethylhexedrone is part of the well-studied stimulant subgroup.
Structure-Activity & Chemical Similarity Predictions
Based on the chemical similarity of N-Ethylhexedrone with other Cathinone type compounds and the close chemical structure to Hexedrone and Pentedrone, it is believed to act as a stimulant chemical with properties not too dissimilar to other known Cathinones.
It is believed that due to the addition of the Ethyl group to the hexedrone core, the subjective potency of affinity to stimulant receptors would be markedly increased.
Most likely, it is predicted that N-Ethylhexedrone would act on the dopamine and norepinephrine transporter proteins, mainly as a potent releasing agent and re-uptake inhibitor.
Key Areas of Research
Samples of N-Ethylhexedrone to purchase online may be used in the following scientific applications.
- As a forensic sample and/or for forensic chemical catalogues.
- As a reference sample for Toxicology laboratories.
- As a chemical reagent and/or intermediate
- Pharmaceutical Intermediate
- As a research chemical sample within studying pharmacology of receptor binding assays.
- Effinity and Efficacy Receptor profiling, specifically the DAT and NERT receptors.
- Reference sample for the application within future therapeutic compounds
- Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment
Online Anecdotal Reports
Forum links to anecdotal discussion by those who are able to buy N-Ethylhexedrone (Hex-en) crystals online. There are various online discussions outlining the use of N-Ethylhexedrone’s dosage and reviews, including vendor discussions and anecdotal experience reports on where to buy N-Ethylhexedrone online and the subjective anecdotal reports.
Below are some of the more popular N-Ethylhexedrone discussion pages:
Chemical Safety, Legality & Indented Use
Intended use
This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.
Legality
It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.
Chemical Safety
This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.
Reviews
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