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Semax is also commonly referred to as Semax nasal spray. A neuropeptide  originally developed in Russia, Semax was rigorously tested for 14 years before becoming approved by the Russian Federation Ministry of Public Health and Pharmaceutical Industry.
Benefits and Effects
Semax’s nootropic properties give it the ability to have several positive benefits on users, both physically and cognitively.
Alleviates Stress and Anxiety
Semax is often used as a mood booster or enhancer; it may alleviate feelings of stress and anxiety. Semax may also alleviate chronic stress through interaction with liver enzymes.
Improves Memory Function and Retention
Semax’s heavy metal content may help prevent learning and memory inhibition.  Results suggested that these heavy metals worked similar to ascorbic acid, which also provide antioxidant properties.
Semax may have a positive effect when used as a cognitive booster, helping the user maintain clarity and focus while completing various tasks. This can result in higher levels of productivity as well. 
Potential Treatment of ADHD
Research shows Semax’s potential to enhance the release of dopamine in various parts of the brain as well as to impact the serotonergic brain systems. 
This has been linked to memory improvement and an increase of neurotransmitters that are often required in the treatment of ADHD.
Prevents Oxidative Stress and Damage
Oxidative stress is an imbalance in reactive oxygen species (ROS) and concentrations of antioxidants. Semax can help protect the body from the poisonous effects exposure of lead can have on the brain.
Semax may prevent ROS damage to the body after someone experiences a stroke or heart attack. This has been linked to the drug’s antioxidant behaviour.  
Semax and Pain Relief
Specific Semax doses may reduce the breakdown of Enkephalins – chemicals associated with the body’s response to pain. By maintaining the presence of these chemicals, levels of pain that are perceived can be lessened. 
How Semax Works
The process of Semax is somewhat unclear. Certain studies show that Semax works as an antagonist of the MC4 and MC5 receptors Meaning, Semax interacts with melanocortin receptors. 
Semax is also able to increase neuotrophin production within the brain and to activate the NMDA receptors in the brain for glutamate.
Semax comes in spray form: N Acetyl Semax Amidate, NA Semax Amidate, or simply NA Semax. These function similarly, and are typical forms purchased online for use and nasal administration.
Semax is potent at higher concentrations. Semax nasal spray dosage of 0.5-1.0 milligrams/day is considered average administration.
Differences exist between Semax 0.1% and Semax 1%, and depending on the concentration, the Semax experience will drastically differ. 
Lower Semax spray doses should perform satisfactorily for those looking for mere cognitive benefits.
Semax side effects seem to be minimal. Semax can lead to feelings of energy crashes after prolonged use – as characterized by its antidepressant activity. Minimal long-term Semax research should warrant individuals to exercise caution before considering long-term administration.