Methoxphenidine Chemical Information
Table of Contents
Known Chemical Data
|Systematic (IUPAC) name||(±)-1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine|
|CAS Number||1. 127529-46-8|
|Molar mass||295.426 g/mol|
Methoxphenidine – Discovery, History & Research
Methoxphenidine was first files for patent on the 12th of June 1989 by a team working for G.D. Searle & Co. The patent claims for a novel treatment for neurotoxic injury describing a process for preparing a 1,2-diarylethylamine. Below is a list of the names inventors for patent Application number EP19890110572. The publication of this patent was April 6th 1994.
Inventors: Nancy M. Gray, Brian K. Cheng
From the publication of the patent in 1994, Methoxphenidine has found publications in various major scientific journals, namely Toxicology reports from the introduction of cheap MXP as it was branded online. After receiving a short time of availability online, the UK Arylcyclohexylamine ban in 2013 led to its decreased usage in the proliferating research chemical industry. Since then, China, Sweden and more recently Canada have since issued bans on the compound.
Methoxphenidine research has not been as complete as its chemical cousin – Diphenidine. However, between 2014 and 2015 there have been several published articles relating to test purchases, harm reduction and the general dissociative diarylethylamine class. Due to the nature of the availability of Methoxphenidine in the public domain, much of the research has focused on its misuse and not its potential therapeutic benefit to medicine.
Listed below are some of the more notable publications surrounding Methoxphenidine and its chemical class; arylcyclohexylamines.
Methoxphenidine – Chemical Structural Data
Methoxphenidine is structurally related to Diphenidine with a substituted phenethylamine skeleton incorporating an additional phenyl. Its terminal amino group has a piperidine ring allowing its classification into the piperidine dissociative class. As a chemical analogue of Diphenidine, Methoxphenidine has the additional 2-methocy CH3O- substitution.
Methoxphenidine Structure-Activity & Chemical Similarity Predictions
As a chemical analogue of Diphenidine and with structural relations to the diarylethylamines class, Methoxphenidine has the ability to act as a dissociative anaesthetic with possible analgesic properties hypothesises.
Based on Structure-Activity predictions, Methoxphenidine would act as an NMDA receptor antagonist much like Diphenidine, Methoxetamine and Ketamine. However, as the original patent research suggests that as one of the three isomeric anisyl-substituents the affinity for the NMDA receptor may be higher than that of 4-MeO-Diphenidine but with a lower affinity than 3-MeO-Diphenidine.
Key Areas of Research
Samples of Methoxphenidine to purchase online may be used in the following scientific applications.
- Within forensic sample analysis as an addition the ever growing catalogue of novel compounds.
- As a reference sample for Toxicology laboratories.
- As a chemical reagent and/or intermediate
- Pharmaceutical Intermediate
- As a research chemical sample within the pharmacology of receptor binding assays (specifically NMDA Receptors)
- Reference sample for the application within future therapeutic applications.
- NMDA receptor research.
- Dissociative, analgesic and anaesthetic medicinal research.
- Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment.
Methoxphenidine Online Anecdotal Reports
The online dissociative arena has been extremely prolific since some of the first derivatives of PCP hit the market in 2008. Since then there have been some more notable Ketamine analogues within the grey-market. At least 14 derivatives of Phencyclidine (the first dissociative, 1956). This market has evolved and has over 12 dissociatives.
Methoxphenedine reviews and dosage discussions have proliferated through online forum discussions and research groups. The availability of cheap Methoxphenedine in the USA and UK has opened up various in depth discussion pages. Some of the more popular searches are for obvious comparisons such as Methoxphenidine vs diphenidine, as well as user report requests for Methoxphenedine reddit reviews.
Methoxphenidine Chemical Safety, Legality & Indented Use
This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.
It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.
This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.