Table of Contents
Known Chemical Data
|Systematic (IUPAC) name||N-[(2S)-1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-(cyclohexylmethyl)indazole-3-carboxamide|
|Molar mass||370.497 g/mo|
2. Adb-chminaca, (+/-)-
3. Mab-chminaca, (+/-)-
5. 1H-Indazole-3-carboxamide, N-(1-(aminocarbonyl)-2,2-dimethylpropyl)-1-(cyclohexylmethyl)-
Discovery, History & Research
As part of the ever-growing research chemical movement including many novel cannabinoid synthetic molecules. MAB-CHMINACA was first identified in patent WO2009106980 A3 by Pfizer Inc. back in February 2009 with a publication date only a few months later in October of the same year/
Since it patent and general discovery online there has been some moderate discussion about its usage. It was described as a “Indazole Derivative” and, as such would have found its way into CB1 receptor binding laboratory analysis interested in the effects of synthetic cannabinoids. Since then, it has had some interested by the scientific community and also by the law enforcement of some countries looking to ban its sale online. Some of the more prominent western countries began to ban the substance from around 2104 – 2015, after several toxicity reported deaths.
Much of the research conducted on MAB-CHMINACA has been mainly about its discovery in the online illicit market place, with only a few studies discussing its binding profile.
For more information on some of the more notable papers, please see below:
Cayman Chemical – “MAB-CHMINACA”
Chemical Structural Data
As an indole based synthetic cannabinoid based on the indoazole subgroup, MAB-CHMINICA is structurally related to AB-FUBINACA also sharing a high affinity for the CB1 receptor. MAB-CHMINACA shares a similar cyclohexyle group to its core structure, however, with the difference of having a isobutyl moiety substituted at the at the tert-butyl group.
Structure-Activity & Chemical Similarity Predictions
Being structurally similar to the synthetic cannabinoids, it is predicted that MAB-CHMINACA would have an affinity and possible efficacy at the cannabinoid receptors.
We do have some data on the binding profile seen at the CB1 receptor, provided by in vitro testes conducted at Cayman Chemical.
Key Areas of Research
Samples of MAB-CHMINACA to purchase online may be used in the following scientific applications.
- As a forensic sample and/or for forensic chemical catalogues.
- As a reference sample for Toxicology laboratories.
- As a chemical reagent and/or intermediate
- Pharmaceutical Intermediate
- As a research chemical sample within studying pharmacology of receptor binding assays.
- Affinity and Efficacy Receptor profiling profiling, specifically at the cannabinoid receptor subgroup.
- Reference sample for the application within future therapeutic compounds
- Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment
Online Anecdotal Reports
There are several online discussions where people are confused between MAB-CHMINICA & ADB-CHIMINACA. As these two are the same chemical but can often be confused in the literature.
Further discussion revolves around MAB-CHMINICA reviews, erowid and wiki pages, with more MAB-CHMINICA dose chat and the obvious MAB-CHMINICA experience and effects anecdotal reports.
Forum links to anecdotal discussion by those who are able to buy MAB-CHMINACA crystals online.
Chemical Safety, Legality & Indented Use
This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.
It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.
This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.