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Chemical Information



FUB-APINACA structure


Known Chemical Data


Systematic (IUPAC) nameN-(adamantan-1-yl)-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide
Chemical NameFUB-APINACA
CAS Number 
ATC code 
Chemical data 
Molar mass403.5 g/mol
Online SynonymsFUB-APINACA






Discovery, History & Research


The discovery of  FUB-APINACA or FUB-AKB4 has not official been in the litarature, and like many other “designer drugs” within the synthetic cannabinoid culture, it may well be a product of clandestine laboratory research – looking for a way to modify similar compounds in the light of avoiding analogue acts and research chemical bans.


Since if discussion online FUB-APINACA has been seen in online forum discussion and also in some very interesting studies researching its pharmacology in vivo. From our 2014 to 2016, FUB-APINACA has seen some light online, but with Sweden and the state of Alabama placing in on a controlled substance list around 2014, its production and use in science has tapered off slightly.


Research into FUB-APINACA is limited to mainly “test purchases” conducted by toxicology laboratories and consumer reporters considering “legal highs”

However, there does seem to be some discussion as to the binding affinity of FUB-APINACA at various cannabinoid receptor subgroup.

Below you may find some of the key areas of research regarding FUB-AKB-48 studies.




“Cannabinoider föreslås bli klassade som hälsofarlig vara”. 




Chemical Structural Data

FUB-APINACA is technically an analogue of of its closely related cousin, APINACA and 5F-APINACA. The difference being that the pentyl chain is replaced with a fluorobenzyl. FUB-APINACA is an indole based synthetic cannabinoid.

Structure-Activity & Chemical Similarity Predictions

Much like many of the other similar chemicals within this chemical subgroup, FUB-APINACA has a strong affinity for the CB1 and CB2 receptor subgroup. Interesting there have been some actual pharmacological profiling conducted on FUB-APINACA in vivo, allowing us a small insight into its binding profile at various postulated cannabinoid receptors.


FUB-AKB-48 acts as a full agonist with a binding affinity of 1.06nM at CB1 and 0.174nM at CB2 cannabinoid receptors.


Key Areas of Research


Samples of FUB-APINACA to purchase online may be used in the following scientific applications.  


  • As a forensic sample and/or for forensic chemical catalogues.
  • As a reference sample for Toxicology laboratories.
  • As a chemical reagent and/or intermediate
  • Pharmaceutical Intermediate
  • As a research chemical sample within studying pharmacology of receptor binding assays.
  • Affinity and Efficacy Receptor profiling, specifically CB1 and CB2 receptors.
  • Reference sample for the application within future therapeutic compounds
  • Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment


Online Anecdotal Reports


FUB-AKB48 has been available online from vendors in the USA, UK and various other research chemical vendors up until the last three years. For this reason, online discussion groups such as Reddit and Erowid have large anecdotal, user submitted information surrounding FUB-AKB48 reviews, dosage, experiences and the potential of FUB-AKB48 flashback.


Forum links to anecdotal discussion by those who are able to buy FUB-AKB48 online.










Chemical Safety, Legality & Indented Use


Intended use


This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.


It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.

Chemical Safety

This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.


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