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Dimethylaminoethanol (DMAE), is a chemical that is involved in a succession of reactions which forms acetylcholine. People also search for Deanol and 2 Dimethylaminoethanol when seeking information on this product.
The question, “Where does DMAE come from?”, is frequently asked. It’s found in the brain and other areas of the body in very small amounts. There are a handful of natural resources that are high in DMAE including sardines, salmon, and anchovies. 
DMAE supplements can benefit people who are not fond of the natural resources and those who want the extra benefits that can be obtained from extra DMAE supplementation.
DMAE is necessary for producing the chemical choline. A DMAE choline source can augment the production of acetylcholine, which is one of the body’s most crucial neurotransmitter that aids the function of the brain and nervous system.
It’s intended for many uses like improved memory, enhanced mood, improved reasoning, a sense of well-being, intellectual abilities, and extra energy. DMAE for sleep works very well for many people and some say they have more vivid dreams as well.  
Benefits and Effects
What is DMAE good for?
Brain fog – It is being reported that with DMAE, brain fog is significantly reduced. A study of 612 women, conducted by the University of Michigan Medical School and Depression Center, determined that two-thirds of the women had either major depression or bipolar disorder.  Brain fog is typically present with fibromyalgia as well.
Research and personal testimony of people between the ages of 18 – 99, found that brain fog can frequently be attributed to missing factors in a person’s life including the lack of necessary nutrients that can include DMAE. In addition, a healthy lifestyle can be associated with a lower risk of Alzheimer’s disease and dementia. 
DMAE for Depression and Anxiety – A randomized, double-blind, placebo-controlled study was completed with 80 subjects with threshold emotional disturbances.
The subjects were shown film excerpts that contained various types of emotional content. Some were given DMAE and others a placebo.
Scores revealed a better mood for the active drug group. DMAE can be interpreted to induce a psychophysiological state of better feeling and well-being in subjects suffering from borderline emotional disturbance. 
Many people take DMAE for social anxiety with positive results as well.
Increased energy – DMAE leads to the production of acetylcholine, a very important neurotransmitter that aides the brain and nervous system. It can provide an overall enhancement of physical and mental energy. 
In the central nervous system, acetylcholine is basically “excitability”. It can help the contraction of muscles and could be responsible for helping athletes sustain focus. Athletes and bodybuilders take DMAE bitartrate as a pre-workout supplement. A lack of acetylcholine can cause fatigue, oxygen inefficiency, and muscle weakness.  
Skincare – DMAE is increasingly becoming an ingredient in cosmetics. Growing evidence is being attained about the ability of DMAE to improve skin. There is an indication pointing to acetylcholine as a ubiquitous cytokine-like molecule that regulates cellular processes. 
There is presently an abundance of products with DMAE in them. It’s professed to hydrate, improve texture and tone, firm and smooth, rejuvenate, fade brown spots, and diminish and prevent wrinkles and fine lines to some extent. DMAE gel, cream, lotion, and serum are some of the cosmetic types in which it’s contained.   
In addition, it is receiving very favorable reviews from many women who claim it starts working shortly after applying and continues improving skin health and appearance with long-term use.   
Is DMAE safe for skin? A one-year extension to the trial showed a good safety profile with long-term use. DMAE face cream side-effects are proving to be minor or non-existent in most cases. 
Athletic performance – Many athletes and bodybuilders claim it gives them improved recovery time and performance. The energetic effects of DMAE may enable them to have better stamina as well.  
Where Can I Buy DMAE?
Many people inquire about where to buy DMAE. It is available over-the-counter and online on an assortment of sites; however, PowderCity.com is a favorite due to the quality and variety of their products.
What is DMAE Bitartrate?
DMAE Bitartrate is the powder form of DMAE.
What are DMAE Benefits for Men?
In addition to the physical benefits, some skin care products containing DMAE are available for men including serums. Men are not as likely to want a whole skincare regime to deal with, so all-purpose products are available for them. 
Is DMAE bitartrate banned?
DMAE is not regulated and can be purchased over-the-counter and online.
How Does DMAE Work?
Choline, produced by DMAE, is one of the most critical neurotransmitters for memory storage and retention. DMAE and choline are essential to the brain’s function. They add to the integrity of cell membranes and healthful performance of numerous neural activities. 
DMAE VS Choline Bitartrate
DMAE is deemed to boost acetylcholine levels of the brain by impeding choline metabolism in peripheral tissues.
Choline Bitartrate is choline combined with the salt of tartaric acid. It has a better assimilation rate than pure choline.
DMAE Amine vs DMAE Bitartrate
When making DMAE cosmetics, if you added the amine form, the PH would be too high and would therefore not be suitable for use on skin. It would have to be neutralized. 
Bitartrate already contains tartaric acid, so it would need no other additives.
DMAE Bitartrate VS DMAE
DMAE Bitartrate is the powder form of DMAE.
DMAE Bitartrate VS DMAA
DMAA was touted to be a natural stimulant; however, there has been controversy as to how natural it really is. It was banned in 2017. 
DMAE is not one size fits all, especially when concerning dosage. It can vary from person to person depending on its intended to use.
Additionally, if you plan to use it in a stack, the dosage may need to be adjusted as well.
DMAE liquid, pill, and powder forms can be purchased over-the-counter. The one you use is a personal preference. Some people like the convenience of pills. The powder form, called dimethylaminoethanol bitartrate, benefits many people by mixing a small amount in their morning coffee or tea for an added boost. DMAE vegan supplements are available as well.
The DMAE bitartrate dosage has no recommended dosage and can react differently with each individual person; therefore, start at a lower dose and adjust it to your needs. As with any new supplement, it’s a good idea to discuss dosage with a doctor.
Furthermore, it comes in a very wide range of strengths ranging from 50 mg to 1500 mg. 
It may be advisable to start with 50 to 100 mg once or twice a day. That will let you test if the dosage is appropriate for you or if you have any side-effects. If you tolerate that dosage well but are not receiving any benefits, then increase it gradually until you find the correct dosage for you.
You can also determine if you need to take DMAE with or without food.
Many people are reporting that they are making homemade DMAE serum by mixing 3% or less of the liquid form with baby oil or other oils of their preference. They also mix a small amount with their favorite cream for moisturizing. 
In most studies and personal experiences, DMAE is well tolerated.  Although rare, some dimethylaminoethanol side effects may include:
- gastrointestinal problems
- high blood pressure
With DMAE lotion, side-effects are rare especially since it is an effective anti-inflammatory. However, some people with sensitive skin may occasionally experience irritation and redness typically when the DMAE is combined with other cosmetic ingredients. It is recommended that people with sensitive skin use it every other day until they know their tolerance. 
Women who are pregnant or nursing should not use DMAE at this time until more research is completed.
People with a history of convulsions, epilepsy, or bipolar disorder should consult a doctor before use. It could intensify those conditions.
On rare occasions, increased blood pressure can occur. People with high blood pressure should practice caution. 
The stacks you take can depend on the intended use and other factors. Below are a few possible stacks.
L-Tyrosine, DMAE, Lecithin, and Vitamin B6 – DMAE and Tyrosine can enhance cognitive and physical effects. Lecithin increases good cholesterol and lowers triglycerides. 
A study was conducted with 50 people who instruct sports. They were given a combination of dimethylaminoethanol bitartrate, ginseng, minerals, and vitamins. The DMAE’s before and after results were much better in the subjects who took the stack as compared to a placebo.  
DMAE Bitartrate and choline – These two supplements taken together may provide more oxygen to the brain which further supports healthy brain performance.
DMAE and Alpha GPC – This stack is recommended for increasing energy, cognition, growth hormones, and decreasing cognitive decline, and symptoms of Alzheimer’s disease. Alpha GPC aids choline in bypassing the blood-brain barrier.