Table of Contents
Known Chemical Data
|Systematic (IUPAC) name
Discovery, History & Research
The official patent which would cover the discovery of AB-CHMINACA would be that of Pfizer’s application in February 2009 when patent number WO2009106980 A2 was first described in the literature and later published in September 2009.
Since its documentation in the above mentioned patent there has been much discussion of its use in the scientific community and non-scientific community also. Some studies exist with the use of AB-CHMINACA in vivo on mice, with further documented toxicology reports. Since its discussion began around 2009, its steadily gained popularity as a potent synthetic cannabinoid. Finally, as the legal community began to see AB-CHMINACA deaths the research chemical has become controlled and scheduled in many countries including, USA, Germany, China, and Switzerland in 2015.
AB-CHMINACA has some very interesting studies into its binding affinity in rate, which is rarely seen on novel compounds. It has been found to be extremely potent and fully replace THC as a substitute. Furthermore, research into it’s illicit use has been conducted in various toxicolocy reports after several deaths were reported around the world.
Some of the more notable research papers can be found below.
Chemical Structural Data
AB-CHMINACA is an indole based synthetic cannabinoid. It has a cyclohexyl group substituted for the 4-fluorophenyl group as seen in it’s chemical cousin AB-FUBINACA. As part of its structure, much like other synthetic cannabinoids seen in its generation, it contains a valine amino acid amide residue rather than the more classically seen naphthyl or adamantine residue.
Structure-Activity & Chemical Similarity Predictions
Based on the animal studies available, AB-CHMINACA is highly potent and able to cause psychological effects similar to the THC within herbal marijuana. As a potent agonist at the CB1 receptor and CB2 receptor with Ki values of 0.78 nM and 0.45 nM respectively, it is 16 more potent than THC.
Key Areas of Research
Samples of AB-CHMINACA to purchase online may be used in the following scientific applications.
- As a forensic sample and/or for forensic chemical catalogues.
- As a reference sample for Toxicology laboratories.
- As a chemical reagent and/or intermediate
- Pharmaceutical Intermediate
- As a research chemical sample within studying pharmacology of receptor binding assays.
- Affinity and Efficacy Receptor profiling specifically at the CB1 and CB2 receptors.
- Reference sample for the application within future therapeutic compounds
- Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment
Online Anecdotal Reports
Since various AB-CHMINACA deaths have been reported, great caution should be taken when reading about anecdotal AB-CHMINACA reviews and experiences online. The DEA have changed the AB-CHMINACA legality with many other countries following suit and banning it sale.
Nonetheless, it has been available in various countries as a research chemical and AB-CHMINACA reddit, erowid and other prominent forum discussions exist.
Forum links to anecdotal discussion by those who are able to buy AB-CHMINACA online.
Chemical Safety, Legality & Indented Use
This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.
It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.
This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.