Do you prefer tubs? 100g Phenibut Tub
Nootropics often work by increasing energy to boost concentration and memory. Sometimes, this can leave you feeling jittery or like your mind is running a never ending race. What if you could find a cheap nootropic that gave you a sense of calm and inner peace?
What is Phenibut?
Phenibut (Beta-Phenyl-Gamma-Aminobutyric acid) is a convenient solution for a calming nootropic that helps eliminate the stress and anxiety that can hurt your mental performance. Developed in Russia, Phenibut is a derivative of the neurotransmitter GABA (binding specifically to GABAB receptors). The added phenyl group allows Phenibut to pass through the blood-brain barrier and lowers levels of stress and anxiety.[1, 2]
How Does it Work? Side Effects and Benefits
So if Phenibut works as GABA in the brain, what is so important about GABA? GABA (and again, specifically GABAB) works by opening up potassium channels in a given neuron. This balances the neuron's equilibrium potential in such a way that it decreases the ability for other neurotransmitters to be released and reduces overall activity in the neuron .
In other words, GABA slows down the processes that the targeted neuron is responsible for. This helps to explain the potential anti-anxiety and calming side effects of Phenibut. For example, the Russian Cosmonauts used Phenibut as a way to decrease anxiety without negatively affecting mental acuity.
Phenibut also increases levels of dopamine, a key neurotransmitter for feeling happy and motivated.
This makes Phenibut a very well-rounded calming experience. Luckily, the dopamine activity is low enough to not produce many of the bad side effects for which some dopaminergic drugs (like amphetamines) are notorious.
As far as using Phenibut powder in your daily nootropic stack, there is a wide range of potential. Phenibut is often used to balance out the stimulating effects of some nootropics (caffeine, ampakines, etc.), but can be used on its own for its anxiolytic properties. A typical Phenibut dosage can vary from as little as 200 mg to well over 500 mg. Lower doses are more commonly used earlier in the day to reduce anxiety and any jitters caused by stimulants. User often reserve the higher doses for later in the day to combat sleeplessness.
Phenibut is a great option for anyone wanting a calm head space that still allows them to get things done. Phenibut is also a very inexpensive alternative to L-theanine, an amino acid which also works through GABA and, to a lesser degree, dopamine.
People who take MAO inhibitors, some anti-epileptic drugs, or who might combine Phenibut with alcohol, should consult a health care professional before taking Phenibut.
- Phenibut (β-Phenyl-GABA): A Tranquilizer and Nootropic Drug [pdf]
- Lapin, Slava. From the Inside. Luniver Press. 2009.
- GABA Neurotransmitter
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Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies.
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