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Phenibut HCL

Do you prefer tubs? 100g Phenibut Tub

Nootropics often work by increasing energy to boost concentration and memory. Sometimes, this can leave you feeling jittery or like your mind is running a never ending race. What if you could find a cheap nootropic that gave you a sense of calm and inner peace?

What is Phenibut?

Phenibut (Beta-Phenyl-Gamma-Aminobutyric acid) is a convenient solution for a calming nootropic that helps eliminate the stress and anxiety that can hurt your mental performance. Developed in Russia, Phenibut is a derivative of the neurotransmitter GABA (binding specifically to GABAB receptors). The added phenyl group allows Phenibut to pass through the blood-brain barrier and lowers levels of stress and anxiety.[1, 2]

How Does it Work? Side Effects and Benefits

So if Phenibut works as GABA in the brain, what is so important about GABA? GABA (and again, specifically GABAB) works by opening up potassium channels in a given neuron. This balances the neuron's equilibrium potential in such a way that it decreases the ability for other neurotransmitters to be released and reduces overall activity in the neuron [4].

In other words, GABA slows down the processes that the targeted neuron is responsible for. This helps to explain the potential anti-anxiety and calming side effects of Phenibut. For example, the Russian Cosmonauts used Phenibut as a way to decrease anxiety without negatively affecting mental acuity.[3]

Phenibut also increases levels of dopamine, a key neurotransmitter for feeling happy and motivated.[1]

This makes Phenibut a very well-rounded calming experience. Luckily, the dopamine activity is low enough to not produce many of the bad side effects for which some dopaminergic drugs (like amphetamines) are notorious.[1]


As far as using Phenibut powder in your daily nootropic stack, there is a wide range of potential. Phenibut is often used to balance out the stimulating effects of some nootropics (caffeine, ampakines, etc.), but can be used on its own for its anxiolytic properties.[1] A typical Phenibut dosage can vary from as little as 200 mg to well over 500 mg. Lower doses are more commonly used earlier in the day to reduce anxiety and any jitters caused by stimulants. User often reserve the higher doses for later in the day to combat sleeplessness.

Phenibut is a great option for anyone wanting a calm head space that still allows them to get things done.[1] Phenibut is also a very inexpensive alternative to L-theanine, an amino acid which also works through GABA and, to a lesser degree, dopamine.

People who take MAO inhibitors, some anti-epileptic drugs, or who might combine Phenibut with alcohol, should consult a health care professional before taking Phenibut.

Don't forget to check out our Primaforce Phenibut!


  1. Phenibut (β-Phenyl-GABA): A Tranquilizer and Nootropic Drug [pdf]
  3. Lapin, Slava. From the Inside. Luniver Press. 2009.
  4. GABA Neurotransmitter

Additional Resources

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Reviews for Phenibut HCL
5 out of 5, based on 1 reviews
Abraham Lincoln from US on Aug 14, 2014
Good quality Phenibut and the COA looks good. It looks, smells, tastes, and gives the effects it should. Didn't notice any impurities. One word of caution, Phenibut should not be used as a nootropic. It's highly addictive, builds tolerance quickly, and produces bad withdrawal symptoms in a matter of days. Use 500-1000mg once a week max. There are better things out there for daily use. Be safe and enjoy. :)


Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement or nootropic. Do not take this product if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues.

Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement or nootropic, since there are many unaccounted variables, which fall outside the scope of the studies.

The reviews contained within are the opinions of contributors and are not necessarily the views or opinions of Powder City. These reviews should not be taken as fact or recommendation, and are only opinions of products that the contributors may have or may have not used. Powder City makes no warranty, implied or expressed, to the accuracy of information provided by these reviews.