Pantethine (Pantesin®)

Start an order and find out how to receive free US shipping!
1 review
See all reviews

4978 In stock


As its name implies, pantethine is similar in structure to the essential vitamin pantothenic acid which is known as vitamin B-5. Pantethine metabolizes to pantothenic acid and cysteamine, both of which have powerful benefits. [1]

Dietary sources of this vitamin are plentiful, with avocados, meats, whole grains, eggs, and legumes being the most B-5 rich foods. [2]

Because pantethine metabolizes to pantothenic acid and cysteamine while boasting high bioavailability, supplemental pantethine can fulfill daily vitamin B-5 needs while bringing additional benefits.

Body Composition

Vitamin B-5 is vital for cellular functions of all mammals. [2] Metabolic functions utilize vitamin B-5 to break down proteins, carbohydrates, and fats for energy. [2] Pantethine supplementation can leverage metabolic processes to benefit metabolism.

Pantethine can promote muscle retention and lean mass as well. [3]


By supplementing plasma vitamin B-5 levels, and subsequently CoA, pantethine helps provide key neurotransmitter intermediates. [3] CoA helps carry acyl groups to provide the acetyl- portion of vital neurotransmitters such as acetylcholine and N-Acetylserotonin. [3]

Pantethine vs Pantothenic Acid

Since pantethine is similar to vitamin B-5, you may be wondering why you can’t take vitamin B-5 instead. While vitamin B-5 and pantethine share some benefits, vitamin B-5 cannot exert the same effects on lipids that pantethine can. 

Suggested Dosage

The recommended dosage for our pantethine formulation is 545mg per day. This will yield 300mg of pantethine.


What are some products that go well with pantethine?

Do I need to refrigerate pantethine?

No, you do not need to refrigerate pantethine.

Pantesin® is a registered trademark of Kyowa Pharma Chemical Co., Ltd.



Review guidelines


*Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Consult with your physician before taking if you are pregnant, nursing, have any cardiovascular or other medical issues, or anticipate surgery. Keep out of the reach of children.

Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement or nootropic, since there are many unaccounted variables, which fall outside the scope of the studies.

The reviews contained within are the opinions of contributors and are not necessarily the views or opinions of Powder City. These reviews should not be taken as fact or recommendation, and are only opinions of products that the contributors may have or may have not used. Powder City makes no warranty, implied or expressed, to the accuracy of information provided by these reviews.

Recently Viewed Products