L-Arginine Alpha-Ketoglutarate (AAKG)

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L-Arginine Alpha-Ketoglutarate (AAKG)

Maintaining a peak level of physical fitness requires a significant level of exertion from the body—a level that some struggle to reach without the aid of certain supplements. L-Arginine Alpha-Ketoglutarate, a chemical found in the body, is one such supplement that can help you push past your plateaus and reach your fitness goals [2].

Arginine Alpha Ketoglutarate (AAKG) and Nitric Oxide

L-Arginine Alpha-Ketoglutarate works by increasing the nitric oxide levels in your blood, resulting in dilation of the blood vessels as you workout [1]. For this reason, the supplement is very popular among body builders and those who enjoy extreme workouts, as dilation of blood vessels allows enhanced delivery of oxygen and nutrients to the muscles during exercise [2, 3]. As a result, many feel it improves weight training by providing muscles with greater strength.

L-Arginine Alpha Ketoglutarate also works throughout various body pathways to not only develop muscle, but also heal serious wounds [2].

L-Arginine Alpha-Ketoglutarate (AAKG) Benefits

L-Arginine Alpha Ketoglutarate provides many benefits to the health conscious. Not only does it help to promote increased blood flow to the working muscle, it also helps to reduce the excess ammonia that results from strenuous physical activity [2]. It has also been shown to boost the health of numerous organs including kidneys, liver, and the gastrointestinal tract [2].

There is also evidence that L-Arginine Alpha Ketoglutarate can help with bacterial infections, yeast infections, and eye problems [2]. Additionally, L-Arginine Alpha Ketoglutarate may help protect the heart from damage resulting from poor blood flow and muscle breakdown that comes with surgery or significant physical trauma [3].

L-Arginine Alpha-Ketoglutarate (AAKG) Dosage

The typically recommended dosage for L-Arginine Alpha Ketoglutarate is 2.6 grams, taken as many as three times per day [4]. It is considered safe for adults when utilized properly, and it is not known to have any significant side effects [2, 3]. There are no known supplement or food interactions with this product [3].

CAS Number: 16856-18-1
Synonyms: AAKG, Arginine AKG


  1. http://www.ncbi.nlm.nih.gov/pubmed/21813912
  2. http://www.webmd.com/vitamins-supplements/ingredientmono-144-alpha-ketoglutarate.aspx?activeingredientid=144&activeingredientname=alpha-ketoglutarate
  3. http://www.uofmhealth.org/health-library/hn-4452006
  4. http://www.uofmhealth.org/health-library/hn-4395009#hn-4395009-why-use

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*Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Consult with your physician before taking if you are pregnant, nursing, have any cardiovascular or other medical issues, or anticipate surgery. Keep out of the reach of children.

Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement or nootropic, since there are many unaccounted variables, which fall outside the scope of the studies.

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