Coleus Forskohlii Root Extract 10% (Forskolin)

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Coleus Forskohlii (Forskolin) Defined

Coleus forskohlii is an Ayurvedic herb that produces forskolin. Forskolin increases cyclic adenosine monophosphate (cAMP) which helps with fat loss. [1] Forskolin is able to increase cAMP by stimulating adenylyl cyclase. [2] This, in turn, can increase lipolysis which is the breakdown of fat. [2] According to Ayurvedic tradition, Coleus forskohlii can also improve heart health and more. [3,4]

Coleus Forskohlii Benefits

Coleus Forskohlii and Fat Loss

This herbal supplement has a number of implications for fat loss and body composition. In one study on overweight women, Coleus forskohlii slightly reduced weight. [5] While a slight loss in weight may not seem promising, the control group in the same study gained weight. [5] Coleus forskohlii was able to significantly reduce weight gain. [5]

Coleus forskohlii’s fat loss potential is even greater in men. [6]This is likely because it boosts testosterone which helps with fat loss. [6,7] This same study noted an increase in lean mass and bone mass. [6] Another study found that Coleus forskohlii reduced BMI by 2.38-2.6% over a two month period. [8]

Forskolin and Testosterone

In a study on overweight men, a 250mg dose of Coleus Forskohlii (10% forskolin) increased total testosterone by 16.77+/- 33.77% as compared to the placebo group which lost 1.08+/-18.35%. [6] One possible mechanism of action is that Coleus forskohlii increases cAMP in the testicles. Normally, luteinizing hormone (LH) increases cAMP in the testicles. By sidestepping LH, it is possible to enhance steroidogenesis. [9,10]

This supplement improves lung health as well. It is an effective bronchodilator. [11] This means it opens bronchi and bronchioles, which reduces resistance in the airways and improves airflow to the lungs.

Coleus Forskohlii Synergy

Coleus forskohlii synergizes well with a number of supplements. It pairs well with alpha [2] adrenoceptor antagonists such as Yohimbine. [12] It also goes well with beta-adrenergic agonists like Synephrine as well as Methylxanthines like Caffeine. [13,14]

Coleus Forskohlii Dosage

When dosing forskolin, be sure to use an extract that contains 10% forskolin. Individuals should take 250mg two times per day for a total of 500mg.

Sources

  1. http://www.ncbi.nlm.nih.gov/pubmed/19887595
  2. http://www.ncbi.nlm.nih.gov/pubmed/6289066
  3. http://www.ncbi.nlm.nih.gov/pubmed/6686215
  4. http://informahealthcare.com/doi/pdf/10.1076/phbi.40.2.129.5842
  5. http://www.ncbi.nlm.nih.gov/pubmed/18500958
  6. http://www.ncbi.nlm.nih.gov/pubmed/16129715
  7. http://www.ncbi.nlm.nih.gov/pubmed/25105998
  8. http://www.ncbi.nlm.nih.gov/pubmed/22131759
  9. http://www.ncbi.nlm.nih.gov/pubmed/15037365
  10. http://www.ncbi.nlm.nih.gov/pubmed/15583024
  11. http://www.ncbi.nlm.nih.gov/pubmed/3551340
  12. http://www.ncbi.nlm.nih.gov/pubmed/2881298
  13. http://www.ncbi.nlm.nih.gov/pubmed/2876014
  14. http://www.ncbi.nlm.nih.gov/pubmed/6289066

Additional Resources

Forskolin Extract Examine Page
Forskolin Extract Wiki

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Disclaimer

*Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Consult with your physician before taking if you are pregnant, nursing, have any cardiovascular or other medical issues, or anticipate surgery. Keep out of the reach of children.

Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement or nootropic, since there are many unaccounted variables, which fall outside the scope of the studies.

The reviews contained within are the opinions of contributors and are not necessarily the views or opinions of Powder City. These reviews should not be taken as fact or recommendation, and are only opinions of products that the contributors may have or may have not used. Powder City makes no warranty, implied or expressed, to the accuracy of information provided by these reviews.

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